Dongfang Hotel is situated in the Liuhua Business Circle, a bustling commercial center in Guangzhou. Adjacent to the subway exit, the hotel is only a 30-minute drive from Guangzhou Baiyun Int’l Airport, Guangzhou Railway Station, Guangzhou-Kowloon Station (Guangzhou East Railway Station), Pazhou Exhibition Center of the China Import and Export Commodity Fair, and some venues from the 16th Asian Games.

The airport shuttle bus departs from the hotel every fifteen minutes and can take guests to Guangzhou Baiyun Int’l Airport. An underground parking lot is also available with over 300 parking spaces.